Prioritizing tasks is the norm rather than the exception in my experience. I often use Microsoft Project for overall organization, but I like to be able to quickly access the tasks I need to complete that day or week or in some other timeframe. At the beginning of most days, I make a list of the tasks I must accomplish that day, arranging them based on priority. I use Evernote or something similar so I can easily access my list of tasks from whatever device I'm using. It's an informal system, but it helps me stay focused and productive. I knock the tasks out one-by-one -- or at least accomplish what I can on each task. At the same time, I try to stay flexible to circumstances and open to opportunities to complete tasks faster. For example, a vendor's rep might unexpectedly show up, making it possible to quickly address a task further down my list. Jumping on the lower priority task now will save multiple phone calls and emails -- and lots of time. I'm also open to new information that might change my priorities. I like to balance the need to focus on a task against staying flexible enough to accommodate changing circumstances and priorities. That said, I've learned over the years that it's just as important to know when to say "no" and not get sidetracked when there's something critical to address.